Longevity & aging

# Longevity & Aging Domain Description

Longevity and aging represents the intersection of preventive health and regenerative medicine, focusing on extending both healthspan (years lived in good health) and lifespan through evidence-based interventions. This domain matters because aging is the primary risk factor for most chronic diseases including cardiovascular disease, cancer, neurodegeneration, and metabolic dysfunction. Rather than treating diseases in isolation, the longevity field takes a systems-level approach to slow biological aging processes and maintain cellular function across the lifespan. Research in this space examines mechanisms of aging including mitochondrial dysfunction, cellular senescence, telomere shortening, oxidative stress, inflammation, and loss of proteostasis. Understanding and modulating these processes through supplements and lifestyle interventions represents a paradigm shift from reactive disease treatment to proactive health optimization.