Research

Continuous Glucose Monitoring Shows Promise in Rare Metabolic Disorders; Sleep Apnea Detection Improves With AI

Gut Microbes and Parkinson's: Meta-Analysis Points to FMT as Emerging Strategy

Heart Failure Self-Management Through Digital Tools Shows Real-World Promise

Early Detection Shifts the Needle on Breast Cancer Survival: Meta-Analysis Confirms Screening's Role

Pet Therapy Gains Evidence for Late-Life Depression; Family Support Boosts Breastfeeding Outcomes

Insomnia and poor sleep quality in refugee and asylum-seeking populations: A systematic review and meta-analysis.

A systematic review of 66 studies found that 43% of adult refugees and asylum seekers experience clinically significant sleep disturbances, with mean insomnia scores bordering on moderate clinical sev

Emerging trends and hotspots in cognitive behavioral therapy for chronic pain: a bibliometric analysis.

A bibliometric analysis of 1,070 studies published between 2005 and 2024 reveals that CBT for chronic pain research is accelerating, with emerging focus on digital delivery, treating comorbid conditio

Synergistic Effects of AI-Driven Remote Respiratory Rehabilitation and Cervical Stabilization Exercises on Forward Head Posture, Neck Pain, and Respiratory Function in Older Adults: A Randomized Controlled Trial.

AI-guided respiratory rehabilitation paired with cervical stabilization exercises produced larger improvements in neck pain, headache impact, and respiratory function than cervical exercises alone in

Hospital-Based Psychosocial Case Management and Suicide Prevention in South Korea: A Randomized Clinical Trial.

A structured case management program reduced suicidal thoughts and depressive symptoms in people with major depression and active suicide risk, compared to usual psychiatric care alone [S tier]. The e

Evaluation of a sleep sound analysis smartphone app for home obstructive sleep apnea screening among community-dwelling Chinese adults with hypertension.

A smartphone app analyzing sleep sounds achieved better accuracy than the STOP-BANG questionnaire for identifying moderate-to-severe obstructive sleep apnea in Chinese adults with hypertension [A tier

Enhanced DVT Prevention in Non-ICU Medical Patients: a Cohort Study of IPC Plus LMWH vs. LMWH Alone.

Combined intermittent pneumatic compression (IPC) and low molecular weight heparin reduced deep vein thrombosis risk by 61% compared to heparin monotherapy in high-risk medical patients [A tier], thou

Best evidence summary of digital health interventions for self-management in patients with coronary artery disease.

A systematic review of 38 studies found that digital health interventions can help patients with coronary artery disease improve medication adherence and lifestyle behaviors, though the strength of ev

Comparable Efficacy of Two Anticoagulant Strategies Following Total Hip Replacement in Elderly Patients: A Prospective Randomised Controlled Trial.

In elderly patients undergoing hip replacement, concurrent aspirin plus low-molecular-weight heparin (LMWH) reduced blood clot occurrence to 16% versus 30% with sequential LMWH alone, without increasi

Impact of Early Subcutaneous Basal Insulin With Intravenous Insulin Infusion for Diabetic Ketoacidosis and Glycaemic Outcomes: A Systematic Review and Meta-Analysis.

Adding subcutaneous basal insulin to standard intravenous insulin therapy in diabetic ketoacidosis reduces time to metabolic recovery by approximately 4 hours and modestly decreases fluid requirements

Animal-assisted interventions for depression in older adults: an umbrella review with meta-analysis and trial sequential analysis.

An umbrella review of 27 studies involving 2,156 older adults found that animal-assisted interventions (AAIs) reduced depressive symptoms with a standardized effect size of 0.73, which crosses the thr

Penile augmentation procedures: a systematic review and meta-analysis of techniques, materials, and safety outcomes.

A systematic review of 23 studies found that hyaluronic acid injection had a lower complication rate (9.0%) compared to permanent materials, though all cross-material comparisons relied on indirect ev

Effectiveness of support-based interventions on self-efficacy in patients with diabetes: a systematic review and meta-analysis.

A meta-analysis of six randomized controlled trials found that structured social support interventions significantly improved self-efficacy in diabetes patients [A tier], though the evidence showed su

Individualised Music Playlist Based on the Iso-Principle for De-Escalating Agitation in Older People With Dementia: Protocol for a RCT.

Researchers designed a rigorous trial to test whether music playlists arranged using the Iso-Principle (matching current emotional state then gradually shifting mood) can reduce agitation episodes in

Reproductive tract and follicular fluid microbiota and probiotic interventions in IVF/ICSI outcomes: a systematic review.

A systematic review of 40 studies found that a Lactobacillus-dominant vaginal microbiota, particularly Lactobacillus crispatus, correlates with better IVF/ICSI outcomes, while longer-term probiotic in

Improving Breast Cancer Outcomes by Enhanced Activities in Early Detection and Diagnosis: An Umbrella Review and Meta-Analyses of Randomised Controlled Trials in High-Income Contexts With Universal Healthcare Coverage.

Multiple communication and scheduling interventions boost breast cancer screening uptake, with the strongest evidence for phone counseling, scheduled appointments, and GP-signed reminder letters. [A t