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ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.

© 2026 ProtocolEngine

Research

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Research digests

Evidence updates, new findings, and protocol changes from our research pipeline.

Iron Dosing That Spares the Gut, and a Triglyceride Marker for Gestational Diabetes

Oct 26, 2026· 3 min read

Multi-Risk Follow-Up Gets Trial Protocols, While Berberine Liver Research Expands

Oct 25, 2026· 3 min read

Family Weight Treatment Meets Adolescent Emotion Regulation, and Other Signals From Today's Literature

Oct 24, 2026· 3 min read

Celiac Quality of Life Gaps, Magnesium and Glucose, and What Exercise Does for Cancer Patients

Oct 23, 2026· 3 min read

Staff Conversations on Sexuality, Dentin Microcracks, and Laser Adjuncts: Today's Evidence Scan

Oct 22, 2026· 3 min read

Research updates

A randomized study comparing plant sterol- and soluble fiber-enriched soymilk with plain soymilk in adults with elevated LDL cholesterol.

Oct 26, 2026· 5 min read

title: "Plant Sterol and Soluble Fiber Soymilk Lowers LDL-C More Than Plain Soymilk Over 8 Weeks"

Role of Gut Microbiota-derived Metabolites in the Pathogenesis and Progression of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): A Systematic Review.

Oct 26, 2026· 5 min read

title: "Gut Microbiota Metabolites and MASLD: What a Systematic Review Tells Us"

Pharmacokinetics and Safety Evaluation of the Transglutaminase 2 Inhibitor Suvigletistat in Healthy Chinese, Japanese, and White/European Participants.

Oct 26, 2026· 4 min read

**TL;DR:** In a small Phase I trial of 36 healthy adults, the investigational transglutaminase 2 inhibitor suvigletistat showed similar pharmacokinetics across Chinese, Japanese, and White/European pa

A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.

Oct 25, 2026· 5 min read

title: "A Methodological Framework for an LLM Virtual Companion for Socially Isolated Older Adults"

Association between triglyceride-glucose index (TyG) as a surrogate marker of insulin resistance and risk of gestational diabetes mellitus (GDM): updated systematic review and meta-analysis.

Oct 25, 2026· 5 min read

title: "First-Trimester TyG Index and Gestational Diabetes Risk: A Meta-Analysis"

Myocardial remodelling during sacubitril/valsartan therapy in patients with chronic heart failure.

Oct 25, 2026· 4 min read

title: "Sacubitril/Valsartan vs. Aliskiren: Two Trajectories of Cardiac Remodelling in Chronic Heart Failure"

Lesion Water Content on CT Predicts 12-Month Outcome and Modifies Thrombectomy Effect in Large-Core Stroke-A Secondary Analysis of the TENSION Trial.

Oct 24, 2026· 4 min read

title: "Lesion Water Content on CT Predicts Stroke Outcome After Thrombectomy"

Untargeted metabolomics-based approach to discover biomarkers of apple intake: A randomized controlled trial.

Oct 24, 2026· 5 min read

title: "Urinary Biomarkers of Apple Intake: A Metabolomics Trial Identifies a Four-Metabolite Panel"

Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.

Oct 24, 2026· 6 min read

title: "Search for the HbA1c Target Minimizing Mortality in Type 2 Diabetes: A J-DOIT3 Landmark Analysis"

Incorporating Data From Text Messages and Email Into Psychotherapy: Randomized Controlled Trial.

Oct 23, 2026· 5 min read

title: "Adding Text Message Data to Psychotherapy: What a Randomized Trial Found"

Digital supportive care in prostate cancer: a systematic review.

Oct 23, 2026· 4 min read

**TL;DR:** A systematic review of 88 studies covering nearly 29,000 people with prostate cancer found broad willingness to use digital supportive care tools, valued for convenience and flexibility, th

Global systematic review of how climate change degrades the wellbeing and health of Indigenous children.

Oct 23, 2026· 5 min read

**TL;DR:** A global systematic review of 53 studies finds that Indigenous children across diverse regions are experiencing adverse health outcomes linked to climate change, most consistently through h

Reduced contagious yawning in psychiatric disorders: a systematic review of potential social-cognitive mechanisms.

Oct 22, 2026· 4 min read

**TL;DR:** A systematic review of 23 studies found that contagious yawning is reduced in autism spectrum disorder, psychopathic traits, and schizophrenia-spectrum disorders, but the underlying reasons

Effects of dance-based physical activity on cognitive and psychological health across age groups: a systematic review.

Oct 22, 2026· 5 min read

title: "Dance-Based Physical Activity and Cognitive and Psychological Health Across Age Groups"

Primary healthcare, climate-related health impacts and intercultural dialogue: bibliometric evidence of a fragmented research field.

Oct 22, 2026· 4 min read

title: "Primary Healthcare, Climate Health, and Intercultural Dialogue: A Fragmented Research Field"

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Complete routines combining supplements and habits

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Whole-diet frameworks like Mediterranean, DASH, and MIND