Also known as: UA, mitopure
Latest evidence update: 2026-05-12
Strongest in Replication (69). Held back by Recency (51).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Thousands of participants across the literature.
Mostly aligned, with some divergence.
Evidence base skews older; field may have moved on.
No per-outcome numbers yet for this one. Each finding's direction and strength is shown in the research below.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 500-1000mg daily
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Increases muscle strength and endurance performance in resistance-trained athletes
Improves physical performance and aerobic endurance in middle-aged adults
Enhances mitochondrial health and function in muscle tissue
Associated with better metabolic health markers including lower insulin resistance and waist circumference
Supports immune function by improving T cell and natural killer cell activity