Also known as: UA, mitopure
Latest evidence update: 2026-05-12
Strongest in Study quality (67). Held back by Recency (45).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Thousands of participants across the literature.
Mostly aligned, with some divergence.
Evidence base skews older; field may have moved on.
No per-outcome numbers yet for this one. Each finding's direction and strength is shown in the research below.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 500-1000mg daily
A two-minute quiz builds a daily plan of habits, diet and supplements around your goals and what you already take. Free, no account needed.
Start the quizProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
Increases muscle strength and endurance performance in resistance-trained athletes
Improves physical performance and aerobic endurance in middle-aged adults
Enhances mitochondrial health and function in muscle tissue
Associated with better metabolic health markers including lower insulin resistance and waist circumference
Supports immune function by improving T cell and natural killer cell activity