Also known as: NMN, beta-NMN
Latest evidence update: 2026-12-31
Strongest in Recency (73). Held back by Consistency (55).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Thousands of participants across the literature.
Mixed direction across studies.
Healthy mix of recent and established research.
Effect-size tagged on 147 of 151 claims for this supplement. Our research updates daily; remaining claims are pending re-processing.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 250-500mg daily
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Increases blood NAD+ levels in adults
Does not significantly improve blood sugar control, cholesterol levels, or insulin sensitivity in most adults
Does not improve muscle strength, mass, or physical performance in older adults
May improve aerobic exercise performance and oxygen utilization during training
Increases insulin sensitivity in postmenopausal women with prediabetes