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Evidence-based protocols for every health goal, updated daily.

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ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.

© 2026 ProtocolEngine

Protocols

Step-by-step health routines combining supplements and daily habits. Each step graded by evidence quality.

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Editor's picks

Beginner Starter Stack

The essential foundation — just 4 supplements and 3 habits that cover the most common deficiencies and highest-impact lifestyle changes.

B TIERSleep & recoveryImmune functionCognitive performanceExercise & movement
4 supplements3 habits
Low commitment

Sleep Optimization Protocol

A comprehensive sleep protocol combining supplements and behavioral interventions to improve sleep quality, reduce time to fall asleep, and increase deep sleep duration.

B TIERSleep & recoveryCognitive performanceStress management
4 supplements4 habits
Low commitment
Commitment
Domain

Fix

One-off plans anchored to an event

Sick Day Recovery

Catch a cold or flu early. The Cochrane evidence on zinc lozenges is the headline finding: 75mg+ within 24 hours of onset cuts duration by about a third. Pair with vitamin C and aggressive hydration.

B TIERFix
3 supplements1 habits
One-off plan

Travel & Jet Lag Recovery

Rapid circadian reset protocol for minimizing jet lag and maintaining performance during travel.

B TIERFixSleep & recoveryCognitive performance
4 supplements2 habits
One-off plan

Pre-Workout Protocol

Evidence-based pre-workout stack for energy, focus, and performance without proprietary blends or excessive stimulants.

B TIERFixExercise & movement
5 supplements1 habits
One-off plan

Hangover Recovery Protocol

Evidence-graded pre-game, morning-after, and long-term protocol for hangover recovery. Most of the work is done before you drink.

B TIERFixNutrition & dietSupplementationGut health & microbiome
8 supplements3 habits
One-off plan

All-Nighter Survival

When you have to stay up for a deadline, a delivery, or a launch. Caffeine paced in spaced doses with L-theanine for smoother focus, tyrosine for the cognitive trough at 2-3am, then morning sunlight and a recovery sleep aid the next evening.

B TIERFix
5 supplements2 habits
One-off plan

Big Presentation Prep

Lower the cortisol curve without dulling alertness. Rhodiola two hours out for adaptogen onset, L-theanine plus a small dose of caffeine an hour out for calm focus, hydration and slow nasal breathing right before walking on.

B TIERFix
3 supplements2 habits
One-off plan

Exercise Recovery Protocol

Optimize post-exercise recovery through targeted supplementation, cold/heat therapy, and rest strategies.

B TIERFixExercise & movementMusculoskeletal health
7 supplements2 habits
One-off plan

Long Flight Comfort

Pressurized cabin air dehydrates, oxidizes, and disrupts sleep. NAC and magnesium glycinate just before boarding, melatonin into the sleep window mid-flight, and front-loaded hydration. Pairs with the Jet Lag Recovery plan for post-arrival circadian reset.

A TIERFix
3 supplements1 habits
One-off plan

Protocols

Ongoing daily routines

Fertility & Prenatal Optimization

Preconception protocol supporting egg quality, hormonal balance, and nutritional readiness for pregnancy.

A TIERHormonal healthMetabolic health
6 supplements2 habits
Low commitment

Myopia Progression Slowdown

Evidence-based habits to slow the progression of nearsightedness, especially in children and young adults. The LAMP trial and others show outdoor light exposure as the primary intervention, supported by reduced near-work strain.

C TIERVision & eye health
0 supplements4 habits
Low commitment

Cardiovascular Health Protocol

Heart-protective supplements and exercise targeting blood pressure, cholesterol, and arterial health.

B TIERCardiovascular healthMetabolic health
5 supplements2 habits
Low commitment

Morning Optimization Protocol

Start every day with the right signals — light, movement, cold, and key supplements to set cortisol rhythm and maximize morning energy.

B TIERSleep & recoveryCognitive performanceExercise & movementHormonal healthStress management
3 supplements3 habits
Medium commitment

Digital Wellbeing Protocol

Evidence-based interventions to reduce the negative health effects of screen time, sedentary desk work, and social media. Targets sleep disruption, eye strain, posture, mental health, and physical inactivity from modern digital lifestyles.

B TIERSleep & recoveryCognitive performanceMental health & wellbeingMusculoskeletal health
2 supplements6 habits
Low commitment

Macular Health Protocol

An AREDS2-based protocol for long-term retinal health and reducing the risk of age-related macular degeneration. Built on the largest randomized trial in eye-health research (3,000+ participants, 5-year follow-up).

A TIERVision & eye healthLongevity & aging
6 supplements1 habits
Medium commitment

Skin Health Protocol

Evidence-based supplements and habits for skin elasticity, collagen production, and anti-aging from the inside out.

A TIERSkin, hair & nailsLongevity & aging
4 supplements1 habits
Low commitment

Dry Eye Relief Protocol

A protocol to address chronic dry eye through omega-3 supplementation, daily eyelid hygiene, and environmental adjustments. Combines the mechanical interventions a dry-eye clinic would prescribe with the nutritional support that meta-analyses confirm reduces symptoms.

C TIERVision & eye health
4 supplements8 habits
Low commitment

Screen Eye Strain Relief

A practical protocol to relieve digital eye strain from extended screen time. Combines visual-rest habits that reduce ciliary muscle fatigue with carotenoids that protect retinal cells from blue-light oxidative stress.

C TIERVision & eye healthCognitive performance
3 supplements4 habits
Low commitment

Focus & Productivity Stack

Targeted nootropics and work habits for deep focus, creative output, and sustained mental energy throughout the workday.

B TIERCognitive performanceStress management
5 supplements2 habits
Medium commitment

Foundational Longevity Stack

Core supplements and habits supported by longevity research — targeting NAD+, autophagy, cardiovascular health, and cellular maintenance.

A TIERLongevity & agingCardiovascular healthMetabolic health
5 supplements3 habits
Medium commitment

Evening Wind-Down Protocol

A structured evening routine to transition from high-alert daytime mode to restful sleep preparation.

B TIERSleep & recoveryStress managementMental health & wellbeing
2 supplements3 habits
Low commitment

Mental Health Support

Evidence-based supplements and habits for mood stability, anxiety reduction, and emotional wellbeing.

A TIERMental health & wellbeingStress managementSleep & recovery
4 supplements3 habits
Low commitment

Gut Health Reset

Structured protocol for microbiome diversity, digestion, and gut-brain axis support through targeted supplements and dietary habits.

B TIERGut health & microbiomeImmune functionMental health & wellbeing
4 supplements2 habits
Low commitment

Female Hormone Optimization

Targeted supplements and lifestyle interventions for cycle regularity, PMS relief, and estrogen-progesterone balance throughout every phase.

A TIERHormonal healthMental health & wellbeingExercise & movementSleep & recovery
6 supplements3 habits
Medium commitment

Immune Support Protocol

Evidence-based supplements and habits to maintain robust immune function year-round.

A TIERImmune function
4 supplements2 habits
Low commitment

Beginner Starter Stack

The essential foundation — just 4 supplements and 3 habits that cover the most common deficiencies and highest-impact lifestyle changes.

B TIERSleep & recoveryImmune functionCognitive performanceExercise & movement
4 supplements3 habits
Low commitment

Afternoon Energy Protocol

Evidence-graded protocol that fixes the 3pm crash at its three real causes: caffeine timing, lunch composition, and the circadian dip. Most of it happens at 9am and 12pm, not 3pm.

B TIERCognitive performanceMetabolic healthStress management
4 supplements5 habits
Low commitment

Metabolic Health Optimizer

Blood sugar management, insulin sensitivity, and body composition through supplements and exercise timing.

B TIERMetabolic healthCardiovascular healthExercise & movement
3 supplements4 habits
Medium commitment

Perimenopause & Menopause Support

Evidence-based protocol for managing menopausal symptoms, protecting bone density, and supporting cardiovascular health during hormonal transition.

A TIERHormonal healthMusculoskeletal healthCardiovascular healthMental health & wellbeingSleep & recovery
5 supplements3 habits
Medium commitment

Cognitive Performance Protocol

Evidence-based nootropic stack combined with focus habits for sustained mental clarity, memory, and creative output.

B TIERCognitive performanceStress management
4 supplements2 habits
Low commitment

Stress Resilience Protocol

Adaptogen-based stack with breathwork and cold exposure for HPA axis regulation and stress tolerance.

B TIERStress managementMental health & wellbeingHormonal health
3 supplements4 habits
Medium commitment

Sleep Optimization Protocol

A comprehensive sleep protocol combining supplements and behavioral interventions to improve sleep quality, reduce time to fall asleep, and increase deep sleep duration.

B TIERSleep & recoveryCognitive performanceStress management
4 supplements4 habits
Low commitment

Male Hormone Optimization

Natural approaches to optimizing testosterone through targeted supplements, resistance training, and lifestyle interventions.

B TIERHormonal healthExercise & movementSleep & recovery
5 supplements2 habits
Medium commitment

Budget Optimization Stack

Maximum health impact for minimum cost — only the supplements with the strongest evidence-to-cost ratio.

B TIERImmune functionSleep & recoveryExercise & movement
3 supplements3 habits
Low commitment

Iron & Energy Recovery

Targeted protocol for women with low ferritin, heavy periods, or persistent fatigue from iron-related energy deficits.

B TIERHormonal healthExercise & movementImmune function
4 supplements2 habits
Low commitment