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ProtocolEngine

Evidence-based protocols for every health goal, updated daily.

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ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.

© 2026 ProtocolEngine

Plans for every stage of your health journey

Browse everything for free. Go Premium for personalization. Practitioner Pro for research professionals.

Visitor

No account needed

  • Browse all protocols, supplements, and habits
  • Supplement tier list with evidence grades
  • Take the quiz and see your full personalized protocol
  • Interaction checker and supplement ordering
  • Preset AI questions on every supplement and habit page
Get your protocol
Free account

$0/forever

  • Everything visitors can access
  • Activate and save protocols to your dashboard
  • Build and track your supplement stack
  • Weekly evidence digest email
  • Bookmark articles and research
  • Quiz answers saved to your profile
Create free account
Premium

$12/month

or $99/year (save 31%)

Everything in Free, plus:

  • Sync your protocol to Google Calendar or export as .ics
  • 30 Evidence Assistant questions per day
  • Evidence alerts when new research affects your stack
  • Progress journal — track how you feel, see what's working
  • Smart stack intelligence — synergies, gaps, and conflict alerts
  • Priority access to new features
  • Diet optimization with personalized meal plans and recipes

14 days free. Cancel anytime. 30-day money-back guarantee.

For professionals
Practitioner Pro

€45/month

or €430/year

Everything in Premium, plus:

  • Full database explorer with filter, sort, and join across all data
  • Export filtered views as CSV
  • Unlimited Evidence Assistant questions
  • Cross-reference claims, papers, supplements, and diseases
  • Evidence factor breakdowns for every supplement
  • Shareable protocol links for clients (coming soon)

7-day free trial. 10 Opus reports included.

30-day money-back guarantee

Not satisfied after your trial? We'll refund your first payment in full, no questions asked.

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Frequently asked questions

Can't ChatGPT do this?▾

For one-off questions, sure. But a language model does not remember your stack across sessions, cannot write to your calendar, does not track what you took or how you felt, and does not alert you when new research changes your protocol. ProtocolEngine is the persistent system around the questions, not the answer bot itself. See the full comparison.

What do I get for free?▾

Browse all protocols, supplements, and habits with evidence grades. Take the personalization quiz for a tailored protocol. Use the interaction checker and order supplements via iHerb. Preset AI questions on every detail page. Create a free account to save protocols, build your supplement stack, get weekly evidence digest emails, and bookmark research.

What does Premium unlock?▾

Sync your protocol to Google Calendar or export as .ics. 30 Evidence Assistant questions per day with custom questions. Evidence alerts when new research affects your stack. Progress journal to track how you feel and see what works. Smart stack intelligence with synergy, gap, and conflict alerts. Diet optimization with personalized meal plans and recipes.

Who is Practitioner Pro for?▾

Practitioner Pro is built for health professionals, researchers, and coaches. It includes the full database explorer with advanced filters, CSV export, unlimited Evidence Assistant questions, cross-referencing across claims, papers, supplements, and diseases, and evidence factor breakdowns for every supplement.

How is evidence graded?▾

We use a 7-factor confidence algorithm aligned with the GRADE framework and Cochrane Handbook. Factors: study design (21%), risk of bias (16%), replication (21%), sample size (16%), consistency (11%), precision (5%), and recency (10%). Effect size is reported separately as its own axis. Scores update automatically when new research publishes.

How does the free trial work?▾

Premium includes a 14-day free trial. Practitioner Pro includes a 7-day free trial. You will not be charged until the trial ends. Cancel anytime during your trial and you will not be billed.

Can I cancel anytime?▾

Yes. Cancel your subscription at any time from your dashboard. You keep access until the end of your billing period. No cancellation fees.

Is this medical advice?▾

No. ProtocolEngine provides educational health information based on published research. Evidence grades reflect research quality, not guaranteed outcomes. Always consult a healthcare professional before starting any supplement or protocol.

Where does the research come from?▾

Our automated pipeline ingests from PubMed, bioRxiv, and medRxiv daily. We currently index over 32,000 papers and prioritize meta-analyses, systematic reviews, and randomized controlled trials. Claims are extracted and linked to supplements and habits automatically.