Also known as: quercetin dihydrate
Latest evidence update: 2026-04-25
Strongest in Replication (80). Held back by Recency (33).
Solid mix of RCTs with some methodological gaps.
Confirmed across many independent studies with significant findings.
Tens of thousands of participants pooled across studies.
Mostly aligned, with some divergence.
Mostly pre-2020 research; updates may be needed.
Effect-size tagged on 395 of 400 claims for this supplement. Our research updates daily; remaining claims are pending re-processing.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 500-1000mg daily
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
May modestly lower blood pressure in people with high blood pressure or prehypertension
May reduce cholesterol and triglyceride levels in people with metabolic disorders
Shows promise for reducing arthritis symptoms and inflammatory markers in animal studies
May improve endurance exercise performance and oxygen utilization slightly
Shows antioxidant and anti-inflammatory effects at high doses in people with existing diseases