Also known as: trans-resveratrol
Latest evidence update: 2026-10-22
Strongest in Replication (80). Held back by Recency (30).
Solid mix of RCTs with some methodological gaps.
Confirmed across many independent studies with significant findings.
Tens of thousands of participants pooled across studies.
Mostly aligned, with some divergence.
Mostly pre-2020 research; updates may be needed.
Recommended: 250-500mg daily
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
When used alongside professional deep cleaning, natural products like resveratrol may help reduce gum pocket depth more effectively than deep cleaning alone
When combined with professional deep cleaning, natural products may provide additional improvements in gum inflammation and bleeding
When used alongside professional deep cleaning, natural products may help improve gum attachment levels more effectively than deep cleaning alone
Resveratrol works through antimicrobial, anti-inflammatory, antioxidant, and immune-supporting properties that may benefit gum disease management
Resveratrol does not appear to affect egg cell maturation or chromosomal health in women of advanced maternal age