Also known as: coenzyme Q10, ubiquinone, ubiquinol
Latest evidence update: 2026-05-12
Strongest in Sample size (95). Held back by Recency (17).
Solid mix of RCTs with some methodological gaps.
Confirmed across many independent studies with significant findings.
Tens of thousands of participants pooled across studies.
Mostly aligned, with some divergence.
Mostly pre-2020 research; updates may be needed.
Ubiquinol formulations are absorbed much more effectively by the body compared to ubiquinone formulations
Ubiquinol acts as a powerful antioxidant that may help reduce oxidized cholesterol levels in people with prediabetes
When combined with D-aspartic acid and zinc, ubiquinol may influence testosterone levels and affect semen quality in men with unexplained infertility
Ubiquinol supplementation is well-tolerated with no reported adverse effects in clinical studies
Recommended: 100-200mg daily
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.