Latest evidence update: 2026-12-27
One-off plan, anchored to the night you're going out. We'll generate a calendar file you can drop into Google Calendar, Apple Calendar, or Outlook.
Kickoff. ISSN 2021 sets evidence-based optimal at 3-6 mg/kg for trained users. 100mg is sub-threshold for caffeine-tolerant adults.
10:00 PM
May 21
at start
Synergy with caffeine — Haskell 2008 ratio for calm focus. Maintains the 2:1 theanine:caffeine pairing across all caffeine doses tonight.
10:00 PM
May 21
0m after
Acute dose, NOT chronic 5g/day loading. Per Gordji-Nejad 2024 RCT: 0.35 g/kg cuts cognitive deterioration during 21h sleep deprivation; 0.2 g/kg also beats placebo. Split 10g+10g at +2h if GI-sensitive.
10:00 PM
May 21
0m after
Peak plasma 1-2h; dose ahead of the 2-3am cognitive trough. Per Neri 1995 + DTIC military research, 100-150 mg/kg preserves reaction time during extended wakefulness. Lower flat doses (e.g., 500mg) are ceremonial — under-dosed by ~14x.
11:30 PM
May 21
1.5h after
Midnight refresh, ahead of the 2-3am trough rather than during it.
01:00 AM
May 22
3h after
With midnight caffeine dose.
01:00 AM
May 22
3h after
taper dose
06:00 AM
May 22
8h after
morning anchor
08:00 AM
May 22
10h after
recovery sleep
04:00 PM
May 22
18h after
Opens an .ics file — your calendar app handles the rest. Nothing stored on our side.
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
Caffeine
50mg