Vitamin K2 (MK-7)

Also known as: menaquinone-7, MK-7, K2

Confidence

research strength

ASolid confidence72107 studies referenced

Latest evidence update: 2026-12-13

Strongest in Sample size (95). Held back by Recency (28).

Study quality (37%)

Study design (21%)

Risk of bias (16%)

Solid mix of RCTs with some methodological gaps.

Replication (26%)

Cross-study replication (21%)

Precision (5%)

Confirmed across many independent studies with significant findings.

Sample size (16%)

Tens of thousands of participants pooled across studies.

Consistency (11%)

Mostly aligned, with some divergence.

Recency (10%)

Mostly pre-2020 research; updates may be needed.

Effect by outcome

how big the change is

Musculoskeletal health Cardiovascular health

Common dosage

100-200mcg daily

Description

Directs calcium to bones and teeth, away from arteries. Essential companion to vitamin D3 supplementation.

Safety & interactions

Contraindicated with warfarin. Safe for most people at recommended doses.

Check interactions with other supplements→

Studied for these outcomesFrom our research corpus

Metabolic HealthC1 study
metabolic flexibility

Outcomes this supplement has corpus evidence for. Click any tag to see how it ranks.

What the research shows

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Fermented milk may help your body absorb vitamin K2 and other fat-soluble vitamins more effectively when taken together

moderate evidence1 study:Journal of nutritional science and vitaminology (2026)

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Vitamin K2 supplementation may support muscle recovery after intense resistance exercise

emerging evidence1 study:Medicine and science in sports and exercise (2026)

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Order Vitamin K2 (MK-7)

Recommended: 100-200mcg daily

Broader research on Vitamin K

Vitamin K2 (MK-7) is a form of Vitamin K. The studies above are specifically about Vitamin K2 (MK-7); broader vitamin k research differs in dose and bioavailability and lives on the parent page.

See all Vitamin Kresearch →

Protocols featuring Vitamin K2 (MK-7)

Cardiovascular Health ProtocolBBuilding confidence

Questions about Vitamin K2 (MK-7)

Who has been studied for Vitamin K2 (MK-7)?

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Who should avoid Vitamin K2 (MK-7) based on the safety notes?

Referenced studies (107)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.