Also known as: B vitamins, B-complex
Latest evidence update: 2026-12-30
Strongest in Consistency (95). Held back by Sample size (30).
Solid mix of RCTs with some methodological gaps.
Some independent replication, statistical precision uneven.
Small combined sample; treat as preliminary.
Studies agree on direction of effect.
Healthy mix of recent and established research.
Recommended: 1 capsule daily
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
Reduces stroke risk, particularly in people without chronic kidney disease and those with elevated blood pressure
Improves nerve function and reduces pain in people with diabetic peripheral neuropathy
Supports cognitive function and memory in older adults and those with mild cognitive impairment
Associated with lower dementia and cognitive decline risk, especially when combined with omega-3 fatty acids
May support lower blood pressure and reduced disability in people with multiple sclerosis