Also known as: water intake, electrolytes
Latest evidence update: 2026-04-01
Strongest in Sample size (86). Held back by Recency (54).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Tens of thousands of participants pooled across studies.
Studies agree on direction of effect.
Evidence base skews older; field may have moved on.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Structured water and electrolyte intake for optimal cognitive and physical performance.
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Intravenous hydration significantly reduced the incidence of contrast-induced nephropathy by 42% compared with no hydration in STEMI patients undergoing primary PCI.
Furosemide combined with hydration therapy has no significant effect on the incidence of contrast-induced acute kidney injury (CI-AKI) in patients after coronary intervention.
High-dose statin alone with hydration reduced contrast-induced AKI risk compared to hydration alone.
Aggressive hydration with lactate Ringer solution reduces the incidence of post-ERCP acute pancreatitis compared to placebo.
Device-guided matched hydration added to saline reduces the odds of contrast-induced acute kidney injury compared to saline alone in patients undergoing cardiovascular procedures.