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Curcumin

Also known as: turmeric extract, curcuminoids

AAdequate Evidence78 studies referenced

Common dosage

500-1000mg daily

Category

herb

Description

Active compound in turmeric with potent anti-inflammatory and antioxidant properties. Requires piperine or liposomal form for absorption.

Safety & interactions

Poor bioavailability without piperine/lipid delivery. May interact with blood thinners.
Check all interactions →

Studies on Curcumin (78)

1.

Efficacy of curcumin for the treatment of depressive symptoms: A systematic review and meta-analysis

Al-Karawi D, et al. (2016) · Crit Rev Food Sci Nutr · n=377

Meta-analysisPubMed
2.

Curcumin for arthritis: Does it really work?

Daily JW, et al. (2016) · J Med Food · n=830

Meta-analysisPubMed
3.

A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults.

Cavanah AM (2026) · Nutrients

4.

Effects of Curcumin/Turmeric Supplementation on Kidney Function in Individuals With Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Bahari H (2026) · Endocrinology, diabetes & metabolism

5.

Overall Survival of Glioblastoma Patients Treated With a Combination of 7 Micronutrients: A Nutraceutical Trial.

Rooprai HK (2026) · Anticancer research

6.

Curcumin Supplementation in Critically Ill Patients: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trial.

Arabi SM (2026) · Phytotherapy research : PTR · n=571

7.

Curcumin for the clinical treatment of rheumatoid arthritis: a systematic review and meta-analysis of placebo-controlled randomized clinical trials.

Fan Y (2025) · Frontiers in immunology

8.

Novel immune-modulating formula versus standard formula for gastrointestinal cancer patients at risk of malnutrition undergoing surgery: A pilot randomized controlled trial.

Lakananurak N (2026) · Clinical nutrition ESPEN

9.

Exploring the In Vitro Anticancer Potential of Indonesian Medicinal Plants and Natural Compounds for Breast Cancer Therapy.

Rakhmina D (2025) · Asian Pacific journal of cancer prevention : APJCP

10.

Tetrahydrocurcumin for Major Depressive Disorder with Therapeutic Potential and Mechanistic Insights from Clinical and Preclinical Studies.

Guo Y (2025) · Molecular neurobiology · n=19

11.

Effectiveness of 0.1% triamcinolone acetonide compared with those of other therapies for minor recurrent aphthous stomatitis: a systematic review and meta-analysis of randomized controlled trials.

Al-Zaghruri AS (2025) · BMC oral health

12.

Impact of Curcuma longa L. extract supplementation on the gut microbiota of hemodialysis patients.

Alvarenga L (2026) · Jornal brasileiro de nefrologia

13.

Antihypertensive Effects of Curcumin/Turmeric Supplementation in Prediabetes and Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Bahari H (2026) · Endocrinology, diabetes & metabolism

14.

Effects of curcumin and Curcuma longa extract on inflammatory biomarkers in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE): a systematic review and meta-analysis of randomized controlled trials.

Liu AJ (2025) · Inflammation research : official journal of the European Histamine Research Society ... [et al.]

15.

The Combined Effects of an Anti-Inflammatory Diet and Curcumin Supplementation on Thyroid Function and Lipid Profile in Patients With Hashimoto's Thyroiditis: A Double Blind Randomised Clinical Trial.

Bourbour F (2026) · Endocrinology, diabetes & metabolism

16.

Effect of curcumin on inflammatory markers and disease activity in patients with rheumatoid arthritis: A meta-analysis.

Zhang F (2025) · Medicine

17.

Antidiabetic and Metabolic Effects of Turmeric (Curcuma Longa) in Patients with Type 2 Diabetes Mellitus or Hyperglycemia - A Systematic Meta-Review and Meta-Analysis.

Amgain K (2025) · Journal of Nepal Health Research Council

18.

Efficacy of curcumin/turmeric on inflammation and oxidative stress in prediabetes and type 2 diabetes: a systematic review and dose-response meta-analysis.

Bahari H (2025) · Inflammopharmacology

19.

Adjunctive curcumin nano-micelles reduce overall pruritus intensity in refractory post-burn pruritus: A randomized controlled trial.

Alirezaei L (2025) · Burns : journal of the International Society for Burn Injuries · n=100

20.

Effectiveness of curcumin mouthwash in preventing traumatic ulcers in orthodontic patients.

Somprajob C (2025) · BMC oral health

21.

Effectiveness and safety of turmeric for the treatment of COVID-19: An updated systematic review and meta-analysis of randomized controlled trials.

Sawangjit R (2025) · Complementary therapies in medicine · n=1,407

22.

Effect of nano-curcumin supplementation on liver fibrosis in patients with NAFLD-associated fibrosis: a double-blind randomized controlled trial.

Gerami H (2025) · Scientific reports · n=55

23.

Effect and Safety of Phytosomal Curcumin Supplementation on Migraine Patients: A Randomized, Double-Blind and Placebo-Controlled Trial.

Shojaei M (2025) · Chinese journal of integrative medicine

24.

Curcumin Attenuates Liver Steatosis via Antioxidant and Anti-Inflammatory Pathways in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial.

Yaikwawong M (2025) · International journal of molecular sciences

25.

Effects of Curcuminoids Plus Piperine Co-Supplementation on Serum Lipid Profile in Adults: A Systematic Review and Meta-Analysis of RCTs.

Karimi M (2026) · Lipids · n=1,038

26.

Efficacy and safety of curcumin in patients with hand osteoarthritis: a pilot double-blinded randomised controlled trial.

Tuntiyatorn P (2025) · BMC complementary medicine and therapies

27.

Comparative evaluation of novel nano-herbal and photo-biomodulation therapy for gingivitis in visually impaired children: A randomized controlled study.

Shrutha SP (2025) · Journal of the Indian Society of Pedodontics and Preventive Dentistry

28.

Curcumin Versus Corticosteroids for Symptomatic Oral Lichen Planus: A Systematic Review and Meta-Analysis.

Al-Maweri SA (2025) · Clinical and experimental dental research

29.

Effect of curcumin on fatigue and musculoskeletal health in postmenopausal women: a double-blind randomised controlled trial.

Shabani F (2025) · BMJ open

30.

Comparative Efficacy of Medical Therapies in Reducing the Risk of Postoperative Recurrence in Crohn's Disease: A Systematic Review and Network Meta-Analysis.

Shehab M (2026) · Inflammatory bowel diseases

31.

Benefits of Nanocurcumin on Mortality in Patients with COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Shang W (2026) · Journal of integrative and complementary medicine

32.

Investigating the Potential of Curcumin in the Treatment of Nonsmall Cell Lung Cancer: A Systematic Review With Meta-Analysis, Network Pharmacology, and Mendelian Randomization.

Guo Y (2025) · Phytotherapy research : PTR

33.

Effectiveness and mechanisms of curcumin for colorectal cancer in preclinical models:A systematic review and meta-analysis.

Jia Y (2026) · Journal of ethnopharmacology

34.

Efficacy and Safety of Curcumin as an Adjuvant to Standard Chemotherapy in Advanced and Metastatic Breast Cancer Patients: A Randomized Controlled Study.

Goyal S (2025) · Phytotherapy research : PTR

35.

Anti-Inflammatory, Antithrombotic and Antioxidant Efficacy and Synergy of a High-Dose Vitamin C Supplement Enriched with a Low Dose of Bioflavonoids; In Vitro Assessment and In Vivo Evaluation Through a Clinical Study in Healthy Subjects.

Chrysikopoulou V (2025) · Nutrients

36.

Evaluation of oral nano-curcumin formulation effectiveness in patients with mild to moderate ulcerative colitis: a randomized, placebo-controlled, double-blind clinical trial.

Ebrahimi Daryani N (2026) · Naunyn-Schmiedeberg's archives of pharmacology · n=43

37.

The effect of turmeric/curcumin supplementation on anthropometric indices in subjects with prediabetes and type 2 diabetes mellitus: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.

Moradi Baniasadi M (2025) · Nutrition & diabetes

38.

Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.

Zhang Y (2025) · Nutrients · n=4,599

39.

The dose-response effects of hydrolyzed curcumin on recovery, inflammation, and oxidative stress following exercise-induced muscle damage in males.

Helder TA (2025) · Physiological reports

40.

Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.

Wu D (2025) · Frontiers in immunology

41.

Curcumin supplementation improves the clinical outcomes of patients with diabetes and atherosclerotic cardiovascular risk.

El-Rakabawy OM (2025) · Scientific reports

42.

The effectiveness and safety of nanocurcumin supplementation for diabetic peripheral neuropathy in patients with type 2 diabetes: a randomized double-blind clinical trial.

Mansour A (2025) · Nutrition journal

43.

Twelve-Week Curcumin Supplementation Improves Glucose Homeostasis and Gut Health in Prediabetic Older Adults: A Pilot, Double-Blind, Placebo-Controlled Trial.

Lamichhane G (2025) · Nutrients · n=23

44.

Curcumin Supplementation Improves Gastrointestinal Symptoms in Women with Severe Obesity: A Double-Blind, Randomized, Placebo-Controlled Trial-A Pilot Study.

Kattah FM (2025) · Nutrients

45.

Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.

Hsueh HC (2025) · BMC complementary medicine and therapies

46.

Targeting cognitive aging with curcumin supplementation: A systematic review and meta-analysis.

Yu L (2025) · The journal of prevention of Alzheimer's disease

47.

Curcumin for Inflammation Control in Individuals with Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Controlled Trial.

Yaikwawong M (2025) · Nutrients · n=78

48.

Effect of a combination of C. longa and B. serrata extracts on hand osteoarthritis. Results of a double-blind, randomized, placebo-controlled, multicenter trial.

Henrotin Y (2025) · Osteoarthritis and cartilage

49.

Therapeutic effects of curcumin and piperine combination in critically ill patients with sepsis: a randomized double-blind controlled trial.

Alikiaii B (2025) · Trials

50.

Effect of adding fenofibrate versus curcumin to glimepiride in patients with type 2 diabetes: a randomized controlled trial.

Nada EM (2025) · BMC pharmacology & toxicology

51.

Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-Analysis.

Miao R (2025) · Phytotherapy research : PTR · n=1,337

52.

Mental health and health-related quality of life response to curcumin-probiotic drink powder co-supplementation in adults with overweight/obesity and metabolic syndrome: a four-arm randomised, double-blind, placebo-controlled, clinical trial.

Mohsenpour MA (2025) · The British journal of nutrition · n=104

53.

Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis.

Cheng YC (2025) · Psychological medicine

54.

Efficacy of curcumin supplementation for the treatment and prevention of pouchitis after ileal pouch-anal anastomosis: a randomized controlled trial.

He AQ (2025) · European journal of nutrition

55.

The effect of curcumin on postpartum depression and anxiety in primiparous women: a double-blind randomized placebo-controlled clinical trial.

Hamlbar EP (2025) · BMC complementary medicine and therapies

56.

Analgesic Efficacy of Bromelain and Bromelain Plus Turmeric for Pain Control After Orthodontic Separator Placement: A Triple-Blind Randomized Clinical Trial.

Ajami S (2025) · Clinical and experimental dental research

57.

Comparison of the antimicrobial effects of 0.2% curcumin mouthwash and chlorhexidine mouthwash on Streptococcus mutans in orthodontic patients: a randomized clinical trial.

Etezadi T (2025) · General dentistry

58.

The effect of highly bioavailable forms of curcumin on lipoprotein(a) plasma levels: A systematic review and meta-analysis of randomized clinical studies.

Fogacci F (2025) · Prostaglandins & other lipid mediators

59.

Role of oral bio-enhanced curcumin in dry eye disease.

Kapil D (2025) · Indian journal of ophthalmology

60.

Add-on effect of curcumin to dienogest in patients with endometriosis: a randomized, double-blind, controlled trial.

Sargazi-Taghazi M (2025) · Phytomedicine : international journal of phytotherapy and phytopharmacology

61.

Topical Curcumin for Prevention of Radiation-Induced Dermatitis: A Pilot Double‑Blind, Placebo‑Controlled Trial.

Heydari B (2025) · Cancer investigation

62.

Effect of hyaluronic acid gel with and without metronidazole on healing of extraction sockets in diabetic patients-a randomized controlled study.

Nityasri A (2025) · Oral and maxillofacial surgery

63.

The Effects of Curcuminoids Supplementation on Serum Adipokines: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials.

Bahrami LS (2025) · Phytotherapy research : PTR

64.

The effects of nanocurcumin on immune-related factors in the ankylosing spondylitis patients: a double-blind, randomized, placebo-controlled clinical trial.

Jaafar HM (2025) · Molecular biology reports

65.

Effects of Curcumin on Postmenopausal Women's Health: A Systematic Review and Meta-Analysis.

Jin D (2025) · Phytotherapy research : PTR · n=982

66.

Nanomicelle curcumin improves oxidative stress, inflammatory markers, and assisted reproductive techniques outcomes in endometriosis cases: a randomized clinical trial.

Jannatifar R (2025) · Naunyn-Schmiedeberg's archives of pharmacology

67.

An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Controlled Trials Investigating the Effect of Curcumin Supplementation on Lipid Profiles.

Unhapipatpong C (2025) · Nutrition reviews

68.

A clinical trial of curcumin effect in comparison to metronidazole on the treatment of bacterial vaginosis.

Mohamadi S (2025) · Scientific reports

69.

The effect of oral curcumin on vincristine-induced neuropathy in pediatric acute lymphoblastic leukemia: A double-blind randomized controlled clinical trial.

Eghbali A (2025) · BMC cancer

70.

The effect of turmeric-Boswellia formulation (Rhuleave-K) in posture-related low back soreness and discomfort: A randomized double blinded placebo controlled trial.

Gupta A (2025) · Journal of back and musculoskeletal rehabilitation · n=52

71.

Influence of phytosomal curcumin on anthropometric indices for nonalcoholic fatty liver disease: A meta-analysis.

Liu N (2024) · Medicine

72.

Curcumin Supplementation as a Preventive Strategy Against Tamoxifen-Induced Nonalcoholic Fatty Liver Disease in ER+ Breast Cancer Patients: A Triple-Blind Randomized Placebo-Controlled Trial.

Hemati S (2025) · Journal of dietary supplements · n=44

73.

Comparative evaluation of the efficacy of herbal and benzydamine mouthwashes in preventing radiation-induced oral mucositis among head and neck cancer patients: a systematic review and network meta-analysis.

Mohandas R (2025) · Evidence-based dentistry

74.

Curcumin plus piperine improve body composition in patients with inflammatory bowel disease: a randomized, double-blind, placebo-controlled clinical trial.

da Paz Martins AS (2025) · European journal of nutrition · n=58

75.

Effects of nanocurcumin supplementation on metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials.

Wilar G (2025) · Pharmacological research

76.

Does curcumin supplementation affect inflammation, blood count and serum brain-derived neurotropic factor concentration in amateur long-distance runners?

Bańkowski S (2025) · PloS one · n=15

77.

Weighing up the potential of "superfoods" compounds of green tea or turmeric as adjuncts in comparison to established therapeutical approaches for periodontal disease.

Heuzeroth G (2025) · Clinical oral investigations

78.

The influence of food matrices on the bioavailability of curcuminoids from a dried colloidal turmeric suspension: a randomized, crossover, clinical trial.

Schönenberger KA (2025) · Food & function

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