Also known as: hydrolyzed collagen, collagen peptides, collagen protein
Latest evidence update: 2026-05-06
Strongest in Sample size (89). Held back by Recency (47).
Solid mix of RCTs with some methodological gaps.
Confirmed across many independent studies with significant findings.
Tens of thousands of participants pooled across studies.
Studies agree on direction of effect.
Evidence base skews older; field may have moved on.
Recommended: 10-15g daily
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
Collagen peptides in processed form are better absorbed by the body compared to native collagen
Collagen mesotherapy injections may help reduce neck pain and disability in people with chronic neck muscle pain
Collagen mesotherapy appears to be safe with no reported side effects in studies of chronic neck pain
Blood markers of inflammation do not reliably indicate whether collagen treatments are working for neck pain
Collagen peptides may help reduce weight gain when consumed as part of a high-calorie diet in animal studies