Also known as: withania somnifera, KSM-66, Sensoril, ashwagandha
Latest evidence update: 2026-11-05
Strongest in Consistency (88). Held back by Recency (42).
Solid mix of RCTs with some methodological gaps.
Confirmed across many independent studies with significant findings.
Thousands of participants across the literature.
Studies agree on direction of effect.
Evidence base skews older; field may have moved on.
Effect-size tagged on 390 of 400 claims for this supplement. Our research updates daily; remaining claims are pending re-processing.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 300-600mg daily
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
Reduces stress and anxiety symptoms in adults with mild to moderate stress
Improves mood, emotional well-being, and happiness
Enhances recovery and reduces muscle soreness in athletes
Improves sleep quality
Supports cognitive function and memory in adults with mild cognitive impairment