Also known as: chasteberry, vitex agnus-castus, chaste tree berry
Latest evidence update: 2025-01-01
Strongest in Consistency (74). Held back by Recency (13).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Thousands of participants across the literature.
Mostly aligned, with some divergence.
Mostly pre-2020 research; updates may be needed.
Effect-size tagged on 108 of 110 claims for this supplement. The corpus updates daily; remaining claims are pending re-processing.
Recommended: 20-40mg daily
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Significantly reduces premenstrual syndrome symptoms including mood changes, bloating, breast tenderness, and headaches
Relieves cyclic breast pain and tenderness in women of reproductive age
Works as effectively as common medications for treating cyclic breast pain, including dopamine agonists, NSAIDs, hormonal contraceptives, and antidepressants
Does not significantly reduce heavy menstrual bleeding compared to placebo
Is generally well-tolerated with only mild and reversible side effects, though nausea and abdominal pain have been reported in some users