Also known as: vitamin b1, B1, thiamine HCl, thiamine mononitrate, benfotiamine, thiamine
Strongest in Sample size (78). Held back by Recency (39).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Tens of thousands of participants pooled across studies.
Mixed direction across studies.
Evidence base skews older; field may have moved on.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 100-300mg the morning after drinking (or higher in chronic alcohol context, medical supervision)
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.