Also known as: broccoli sprout extract, SFN
Latest evidence update: 2026-02-01
Strongest in Replication (70). Held back by Recency (21).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Thousands of participants across the literature.
Mostly aligned, with some divergence.
Mostly pre-2020 research; updates may be needed.
No per-outcome numbers yet for this one. Each finding's direction and strength is shown in the research below.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 10-50mg sulforaphane (or 100-400mg broccoli sprout extract)
ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.
Improves cholesterol and triglyceride levels in animal studies of high-fat diet conditions
May reduce symptoms and improve behavior in people with autism spectrum disorder
Reduces markers of cellular damage and oxidative stress in the liver and supports liver health
May slow abnormal cell growth in lung tissue of former smokers at high risk for cancer
Shows potential to protect the body against damage from air pollution and viral infections