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Not recommended

Human studies show no meaningful benefit, potential harm, or the risks outweigh any possible upside. Better alternatives exist.

Prickly Pear Extract (Opuntia ficus indica)

Also known as: opuntia ficus indica, opuntia, nopal, prickly pear cactus extract

EInsufficient00 studies referenced

Common dosage

1600mg standardized extract, 5 hours before drinking

Description

Anti-inflammatory cactus extract. Single landmark RCT (Wiese et al., Tulane/UCSF, n=55, Archives of Internal Medicine 2004): 1600mg standardized extract 5 hours before drinking halved the risk of severe hangover; significantly reduced nausea, dry mouth, anorexia. CRP 40% lower. Strongest single-ingredient human RCT in the hangover literature.

Safety & interactions

Generally well-tolerated. May cause mild GI effects. Possible additive blood glucose lowering with antidiabetic medications.

Check interactions with other supplements→

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Order Prickly Pear Extract (Opuntia ficus indica)

Recommended: 1600mg standardized extract, 5 hours before drinking

Protocols featuring Prickly Pear Extract (Opuntia ficus indica)

Hangover Recovery ProtocolBBuilding Evidence

Questions about Prickly Pear Extract (Opuntia ficus indica)

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ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.