⚠️

Not recommended

Human studies show no meaningful benefit, potential harm, or the risks outweigh any possible upside. Better alternatives exist.

C60 (Fullerene)

Also known as: fullerene, buckminsterfullerene, c60 olive oil, carbon 60

Confidence

research strength

EInsufficient evidence144 studies referenced

Latest evidence update: 2026-05-04

Strongest in Consistency (35). Held back by Sample size (5).

Study quality (37%)

Study design (21%)

Risk of bias (16%)

Limited to weak study designs or thin reporting.

Replication (26%)

Cross-study replication (21%)

Precision (5%)

Few independent replications; results not yet robust.

Sample size (16%)

Small combined sample; treat as preliminary.

Consistency (11%)

Mixed direction across studies.

Recency (10%)

Mostly pre-2020 research; updates may be needed.

Effect by outcome

how big the change is

No quantified outcomes yet. Once we have studies with measurable endpoints, you will see per-outcome magnitude here.

Longevity & aging

Common dosage

Reported research doses: 1.7 mg/kg in rats; no human dosing standard exists

Description

Spherical carbon molecule (60 atoms) with potent free-radical scavenging properties. Famous for a 2012 rat study reporting near-doubled lifespan when dissolved in olive oil. No human supplementation trials exist; long-term safety is unknown.

Safety & interactions

No human safety trials. The lifespan-extension result has not been independently replicated. Quality of consumer products is unregulated; some preparations have shown phototoxicity concerns.

Check interactions with other supplements→

Some links on this page may earn us a commission at no extra cost to you. This never influences our evidence grades or recommendations. Full disclosure

Order C60 (Fullerene)

Recommended: Reported research doses: 1.7 mg/kg in rats; no human dosing standard exists

Build your Longevity & Aging protocol

A two-minute quiz builds a daily plan of habits, diet and supplements around your goals and what you already take. Free, no account needed.

Start the quiz

Questions about C60 (Fullerene)

Who should avoid C60 (Fullerene) based on the safety notes?

What dose did studies use for C60 (Fullerene), and when was it taken?

What kinds of studies back C60 (Fullerene)?

Referenced studies (4)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.