Also known as: Nigella sativa, black cumin seed oil, thymoquinone
Latest evidence update: 2026-03-29
Strongest in Consistency (88). Held back by Recency (21).
Solid mix of RCTs with some methodological gaps.
Good cross-study replication, some imprecision.
Tens of thousands of participants pooled across studies.
Studies agree on direction of effect.
Mostly pre-2020 research; updates may be needed.
Effect-size tagged on 234 of 241 claims for this supplement. Our research updates daily; remaining claims are pending re-processing.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
Recommended: 1-3g oil daily or 200-600mg thymoquinone extract
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Reduces inflammation markers and improves antioxidant protection in the body
Helps lower blood sugar levels and improve blood sugar control in people with metabolic conditions
Reduces triglycerides and LDL cholesterol while lowering total cholesterol levels
Supports modest weight loss and reduction in body mass index
May help lower blood pressure in people with metabolic conditions