Honest comparison

Why not just use Superpower?

Superpower combines lab testing, a care team and a protocol in one US membership. ProtocolEngine gives you an evidence-graded protocol first, wherever you live.

Choose Superpower if

You live in one of the 41 US states it serves and want 100+ biomarkers, a care team and access to prescriptions, at one of the lowest prices for a full panel.

Choose ProtocolEngine if

You want a protocol before any blood draw, you live in Germany or the EU, or you want each recommendation shown with its evidence grade and papers.

Superpower and ProtocolEngine, side by side

Orders lab tests for youSuperpower is ahead
Superpower
Yes: Yes. 100+ biomarkers (including calculated ones), plus a follow-up test for new members.
ProtocolEngine
No: No. Upload results from any lab you already use.
Clinician review or prescriptionsSuperpower is ahead
Superpower
Yes: Yes. A care team is part of the membership, and prescriptions are available through its marketplace.
ProtocolEngine
No: No. ProtocolEngine provides information, not medical care.
Personal plan from your goals and routines
Superpower
Yes: Yes. Diet, lifestyle and supplements, updated as your data changes.
ProtocolEngine
Yes: A two-minute quiz builds a daily protocol around your goals, schedule and what you already take.
Get a plan without buying a test first
Superpower
No: No. The protocol starts from your blood results.
ProtocolEngine
Yes: Yes. The quiz builds your protocol right away. Lab results add detail when you have them.
Evidence grade on each recommendation, linked to the papers
Superpower
Not shown per recommendation on its public pages. We could not review the logged-in product.
ProtocolEngine
Yes: Each graded supplement, habit and diet item shows its grade from S to E. Click it to see each paper and how it scored.
Earns nothing from what it recommends
Superpower
Runs a marketplace of third-party supplements, peptides and prescription products. It says it sells no own-brand products, adds no extra margin and does not pay doctors on sales.
ProtocolEngine
Partly. We make and sell no supplements, but some shop links are affiliate links. Links never change a grade.
Available in Germany and the EU, in German and French
Superpower
No: No. US only (41 states and DC), in English.
ProtocolEngine
Yes: Yes. Available in English, German and French. Account data is stored in the EU.
Price
Superpower
$199 a year. At-home draws and add-on tests extra.
ProtocolEngine
Free to browse and to take the quiz. Premium: $12/mo or $99/yr

What you get	Superpower	ProtocolEngine
Orders lab tests for youSuperpower is ahead	Yes: Yes. 100+ biomarkers (including calculated ones), plus a follow-up test for new members.	No: No. Upload results from any lab you already use.
Clinician review or prescriptionsSuperpower is ahead	Yes: Yes. A care team is part of the membership, and prescriptions are available through its marketplace.	No: No. ProtocolEngine provides information, not medical care.
Personal plan from your goals and routines	Yes: Yes. Diet, lifestyle and supplements, updated as your data changes.	Yes: A two-minute quiz builds a daily protocol around your goals, schedule and what you already take.
Get a plan without buying a test first	No: No. The protocol starts from your blood results.	Yes: Yes. The quiz builds your protocol right away. Lab results add detail when you have them.
Evidence grade on each recommendation, linked to the papers	Not shown per recommendation on its public pages. We could not review the logged-in product.	Yes: Each graded supplement, habit and diet item shows its grade from S to E. Click it to see each paper and how it scored.
Earns nothing from what it recommends	Runs a marketplace of third-party supplements, peptides and prescription products. It says it sells no own-brand products, adds no extra margin and does not pay doctors on sales.	Partly. We make and sell no supplements, but some shop links are affiliate links. Links never change a grade.
Available in Germany and the EU, in German and French	No: No. US only (41 states and DC), in English.	Yes: Yes. Available in English, German and French. Account data is stored in the EU.
Price	$199 a year. At-home draws and add-on tests extra.	Free to browse and to take the quiz. Premium: $12/mo or $99/yr

Check our side yourself

47,268

papers analyzed and graded so far

456

new papers added in the last 7 days

How every grade is calculated Today's research digest Try the interaction checker

Use both, if you can

Superpower measures and supports. ProtocolEngine grades the evidence behind each option, so you can see how strong it is before you buy anything.

Outside the US, start with the quiz. When you have lab results from any provider, upload them.

Build your protocol in 2 minutes See pricing

Facts about Superpower were checked against Superpower's own website on October 18, 2026. Prices and features change, so check their site before you buy.

Spotted something out of date or unfair? Tell us and we will correct it: hello@protocolengine.io

ProtocolEngine makes and sells no supplements. Some shop links elsewhere on the site are affiliate links; they never change a grade. ProtocolEngine provides general information based on published research. It is not medical advice, diagnosis or treatment. Affiliate disclosure

Superpower is a name or trademark of its owner, used here only to refer to it. ProtocolEngine is not affiliated with or endorsed by Superpower.

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