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Zinc

Also known as: zinc picolinate, zinc bisglycinate, zinc citrate

SStrong Evidence26 studies referenced

Common dosage

15-30mg daily

Category

mineral

Description

Essential mineral for immune function, testosterone production, wound healing, and taste/smell. Many adults are mildly deficient.

Safety & interactions

Don't exceed 40mg/day long-term. Take with food to avoid nausea. Competes with copper — supplement copper if taking >30mg.
Check all interactions →

Studies on Zinc (26)

1.

Zinc and its importance for human health

Roohani N, et al. (2013) · J Res Med Sci

ReviewPubMed
2.

Zinc lozenges and the common cold: a meta-analysis

Hemilä H (2017) · J R Soc Med · n=575

Meta-analysisPubMed
3.

Time-dependent efficacy of zinc supplements in preventing oral mucositis after chemoradiotherapy: a meta-analysis.

Wang J (2026) · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

4.

The Combined Use of Hydroxymethylbutyrate and Branched-Chain Amino Acids to Counteract Uremic Sarcopenia.

Marrone G (2026) · Nutrients

5.

Influencing factors of neural tube malformation: a systematic review and meta-analysis.

Wu X (2025) · African health sciences

6.

Zinc status following different bariatric procedures: systematic review and meta-analysis.

Zhu C (2026) · Annals of medicine

7.

Zinc deficiency and zinc/copper ratio imbalance in autism spectrum disorder: a reanalysis of six multinational studies.

Bjørklund G (2026) · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

8.

The Effects of Salt Fortified with Multiple Nutrients on Health Outcomes in Children, Adolescents, and Adults: A Systematic Review and Meta-Analysis.

Lall G (2026) · Advances in nutrition (Bethesda, Md.)

9.

Adherence to oral zinc supplementation in the management of acute diarrhoeal disease among under-5 children: A systematic review and meta-analysis.

Pradhan SK (2025) · Epidemiology and infection

10.

Prenatal and preschool micronutrient supplementation and behavioral outcomes in school-aged children in Nepal-a cohort study.

Christian P (2025) · The American journal of clinical nutrition

11.

Zinc adjuvant treatment in SARS-CoV-2: A randomized clinical trial.

Gómez-Zorrilla S (2025) · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

12.

The Efficacy of Zinc Supplementation Alone or in Combination for Improving Pregnancy and Infant Outcomes: A Systematic Review and Meta-Analysis.

Diao S (2025) · Journal of evidence-based medicine

13.

Effect of zinc supplementation on premenstrual symptoms: A systematic review and meta-analysis.

Kim YM (2025) · Women & health

14.

Zinc Supplementation on Growth Performance, Mineral Metabolism and Nutrient Digestibility in Lambs: a Systematic Review and Dose-response Meta-analysis.

Darabi M (2026) · Biological trace element research

15.

Efficacy of zinc sulfate supplementation in managing neonatal hyperbilirubinemia: a meta-analysis.

Ghadirzadeh B (2025) · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

16.

Association between markers of female adiposity and live birth among patients undergoing fertility treatment or attempting unassisted conception.

Lee IT (2025) · Human reproduction (Oxford, England)

17.

A systematic review and meta-analysis examining the role of zinc supplementation in ameliorating physical and psychological manifestations of premenstrual syndrome in young females.

Haider S (2025) · European journal of obstetrics, gynecology, and reproductive biology

18.

Zinc Supplementation, Inflammation, and Gut Integrity Markers in HIV Infection: A Randomized Placebo-Controlled Trial.

Baissary J (2025) · Nutrients · n=95

19.

Teach back educational model combined with zinc supplementation improves clinical symptoms and immunity in children with asthma.

Qin Y (2025) · African journal of reproductive health

20.

Evaluation of in vivo supplementation of 2660 mg D-aspartic acid and 200 mg ubiquinol and 10 mg zinc on different semen parameters in idiopathic male infertility: a randomized double blind placebo controlled study.

GamalEl Din SF (2025) · Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica

21.

Antioxidant Supplementation for Management of Gestational Diabetes Mellitus in Pregnancy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

van der Pligt P (2025) · Current nutrition reports

22.

Comparison of Effects of Iron and Multiple Micronutrient Supplementation on Hematological and Growth Indicators among Older Children, Adolescents, and Young Adults in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Zhao A (2025) · Nutrition reviews

23.

Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial.

Upadhyay RP (2025) · The Lancet. Global health

24.

Identifying risk factors for vomiting during diarrhea: A secondary analysis of a randomized trial of zinc supplementation.

Edwards JG (2025) · Journal of pediatric gastroenterology and nutrition

25.

Efficacy of myo-inositol and zinc on insulin resistance in a paediatric population with obesity.

Antoniotti V (2025) · Diabetes, obesity & metabolism

26.

Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis.

Wu R (2025) · Journal of cosmetic dermatology

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.