Citrulline Malate

Also known as: l-citrulline, citrulline, CM

CCautionary5672 studies referenced

Latest evidence update: 2025-08-28

Common dosage

8g citrulline malate (~4g L-citrulline) 60 min pre-exercise

Description

Nitric oxide precursor used acutely pre-exercise for blood flow and resistance-training performance. 2021 meta-analysis (PubMed 34010809) shows significant benefit on repetition performance and reduced post-exercise soreness. Citrulline malate and pure L-citrulline appear equivalent at matched citrulline doses.

Safety & interactions

Generally well-tolerated. May cause mild GI discomfort at high doses. Theoretical interaction with PDE5 inhibitors and nitrates.

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Order Citrulline Malate

Recommended: 8g citrulline malate (~4g L-citrulline) 60 min pre-exercise

Protocols featuring Citrulline Malate

Pre-Workout ProtocolBBuilding Evidence

Questions about Citrulline Malate

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Referenced studies (72)

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