Boswellia

Also known as: Boswellia serrata, Indian frankincense, 5-Loxin, Aflapin

Confidence

research strength

BBuilding confidence705 studies referenced

Latest evidence update: 2026-06-06

Strongest in Recency (100). Held back by Replication (36).

Study quality (37%)

Study design (21%)

Risk of bias (16%)

Mostly meta-analyses and well-designed RCTs.

Replication (26%)

Cross-study replication (21%)

Precision (5%)

Some independent replication, statistical precision uneven.

Sample size (16%)

Thousands of participants across the literature.

Consistency (11%)

Studies agree on direction of effect.

Recency (10%)

100

Most studies are recent (last 2-3 years).

Effect by outcome

how big the change is

No quantified outcomes yet. Once we have studies with measurable endpoints, you will see per-outcome magnitude here.

Directional evidence

Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.

Common dosage

100 to 300 mg standardized Boswellia serrata extract (such as Aflapin or 5-Loxin) daily. Joint relief typically builds over 1 to 3 months.

Description

Boswellia serrata (Indian frankincense) is a resin extract standardized to boswellic acids, used for osteoarthritis and joint pain. Recent network meta-analyses rank it among the most effective supplements for knee osteoarthritis pain and function, with placebo-like tolerability.

Safety & interactions

Generally well tolerated, with mild gastrointestinal upset possible. May interact with drugs processed by the liver, so discuss with a clinician if you take several medications.

Check interactions with other supplements→

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Order Boswellia

Recommended: 100 to 300 mg standardized Boswellia serrata extract (such as Aflapin or 5-Loxin) daily. Joint relief typically builds over 1 to 3 months.

Questions about Boswellia

Who should avoid Boswellia based on the safety notes?

What dose did studies use for Boswellia, and when was it taken?

What kinds of studies back Boswellia?

Referenced studies (5)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.