Boswellia

Also known as: Boswellia serrata, Indian frankincense, 5-Loxin, Aflapin

Confidence

research strength

BBuilding confidence705 studies referenced

Latest evidence update: 2026-06-06

Strongest in Recency (100). Held back by Replication (36).

Study quality (37%)

Study design (21%)

Risk of bias (16%)

Mostly meta-analyses and well-designed RCTs.

Replication (26%)

Cross-study replication (21%)

Precision (5%)

Some independent replication, statistical precision uneven.

Sample size (16%)

Thousands of participants across the literature.

Consistency (11%)

Studies agree on direction of effect.

Recency (10%)

100

Most studies are recent (last 2-3 years).

Effect by outcome

how big the change is

No quantified outcomes yet. Once we have studies with measurable endpoints, you will see per-outcome magnitude here.

Directional evidence

Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.

Common dosage

100 to 300 mg standardized Boswellia serrata extract (such as Aflapin or 5-Loxin) daily. Joint relief typically builds over 1 to 3 months.

Description

Boswellia serrata (Indian frankincense) is a resin extract standardized to boswellic acids, used for osteoarthritis and joint pain. Recent network meta-analyses rank it among the most effective supplements for knee osteoarthritis pain and function, with placebo-like tolerability.

Safety & interactions

Generally well tolerated, with mild gastrointestinal upset possible. May interact with drugs processed by the liver, so discuss with a clinician if you take several medications.

Check interactions with other supplements→

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Order Boswellia

Recommended: 100 to 300 mg standardized Boswellia serrata extract (such as Aflapin or 5-Loxin) daily. Joint relief typically builds over 1 to 3 months.

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Questions about Boswellia

Who should avoid Boswellia based on the safety notes?

What dose did studies use for Boswellia, and when was it taken?

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Referenced studies (5)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.