Citrus Bergamot

Also known as: bergamot, Citrus bergamia, bergamot polyphenolic fraction, BPF, bergamot extract

Confidence

research strength

BBuilding confidence625 studies referenced

Latest evidence update: 2026-07-01

Strongest in Consistency (95). Held back by Sample size (30).

Study quality (37%)

Study design (21%)

Risk of bias (16%)

Mostly meta-analyses and well-designed RCTs.

Replication (26%)

Cross-study replication (21%)

Precision (5%)

Some independent replication, statistical precision uneven.

Sample size (16%)

Small combined sample; treat as preliminary.

Consistency (11%)

Studies agree on direction of effect.

Recency (10%)

Most studies are recent (last 2-3 years).

Effect by outcome

how big the change is

No quantified outcomes yet. Once we have studies with measurable endpoints, you will see per-outcome magnitude here.

Directional evidence

Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.

Common dosage

Bergamot polyphenolic fraction 500 to 1000 mg daily, standardized to flavonoids, for 4 to 12 weeks. Often combined with artichoke for lipids.

Description

Citrus bergamot is a citrus fruit whose polyphenol-rich extract is taken orally for cholesterol and cardiometabolic health. Trials in people with high cholesterol show lower LDL and triglycerides, though results are weaker in healthy people and in complex combination formulas. This entry covers the oral supplement, not aromatherapy essential oil.

Safety & interactions

Generally well tolerated, with mild heartburn possible. May add to the effect of statins and other lipid-lowering therapy.

Check interactions with other supplements→

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Order Citrus Bergamot

Recommended: Bergamot polyphenolic fraction 500 to 1000 mg daily, standardized to flavonoids, for 4 to 12 weeks. Often combined with artichoke for lipids.

Questions about Citrus Bergamot

Who should avoid Citrus Bergamot based on the safety notes?

What dose did studies use for Citrus Bergamot, and when was it taken?

What kinds of studies back Citrus Bergamot?

Referenced studies (5)

ProtocolEngine provides general health information based on published research. This is not medical advice. Consult a healthcare professional before starting any supplement or health protocol.