Latest evidence update: 2026-02-01
Strongest in Consistency (71). Held back by Replication (54).
Solid mix of RCTs with some methodological gaps.
Some independent replication, statistical precision uneven.
Thousands of participants across the literature.
Mostly aligned, with some divergence.
Healthy mix of recent and established research.
No quantified outcomes yet. Once we have studies with measurable endpoints, you will see per-outcome magnitude here.
Sphaeranthus indicus combined with Garcinia mangostana resulted in statistically and clinically significant weight loss compared to placebo, but these findings should be interpreted cautiously due to limited studies and poor methodological quality.
Mangosteen extract reduces oxidative stress markers in various experimental models.
Mangosteen extract reduces pro-inflammatory cytokines in neuroinflammation models.
Mangosteen xanthones modulate NF-κB and COX-2 pathways in neuroinflammation models.
Mangosteen xanthones suppress inflammatory mediators and enhance cellular resilience.
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