Latest evidence update: 2026-02-17
Strongest in Replication (80). Held back by Recency (42).
Solid mix of RCTs with some methodological gaps.
Confirmed across many independent studies with significant findings.
Tens of thousands of participants pooled across studies.
Mostly aligned, with some divergence.
Evidence base skews older; field may have moved on.
Effect-size tagged on 290 of 293 claims for this food. Our research updates daily; remaining claims are pending re-processing.
Areas where research points to a consistent direction of effect. The strength of evidence is graded; the size of the effect is not quantified.
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Myo-inositol is a naturally occurring sugar commonly found in cereals, corn, legumes and meat that acts as an intracellular mediator of insulin signal.
No significant differences were observed in average keratometry between Epi-Off and Epi-On corneal cross-linking across all follow-up durations.
Maximum keratometry flattening became more pronounced at 1 year post-Epi-Off corneal cross-linking with effect size 0.639.
Maximum keratometry flattening was observed at 6 months in Epi-Off versus Epi-On corneal cross-linking with effect size 0.183.
Central corneal thickness significantly reduced more after Epi-Off treatment compared to Epi-On at 6 months with effect size 0.327.